Neurologist, assistant professor, MD, PhD
Other affiliations : Lyon 1 University, Hospices Civils de Lyon (Center for Sleep medicine and Respiratory Diseases)

  • Study of sleep physiology and of transitions between vigilance states, as well as cognitive correlates of these states, using scalp and intra-cranial EEG.
  • Study of interaction between neurological diseases (epilepsy, stroke…) and sleep
  • Clinical research in neurological sleep disorders (insomnia, hypersomnia, parasomnia)


  • Tankéré P, Taillard J, Armeni MA, Petitjean T, Berthomier C, Strauss M, Peter-Derex L. Revisiting the maintenance of wakefulness test: from intra-/inter-scorer agreement to normative values in patients treated for obstructive sleep apnea. J Sleep Res. 2023 Jun 7:e13961. doi: 10.1111/jsr.13961. Epub ahead of print. PMID: 37287324.
  • Peter-Derex L, Avigdor T, Rheims S, Guénot M, von Ellenrieder N, Gotman J, Frauscher B. Enhanced thalamocortical functional connectivity during REM sleep sawtooth waves. Sleep. 2023 Apr 4:zsad097. doi: 10.1093/sleep/zsad097. Epub ahead of print. PMID: 37014146.
  • Ricordeau F, Bridoux A, Raverot V, Peter-Derex L. Progressive narcolepsy : how to deal with intermediate hypocretin-1 values ? J Clin Sleep Med., 2023 in press
  • Felician J, Galvao F, Lefebvre M, Nourredine M, Peter-Derex L. Association of Delayed Sleep/Wake Rhythm with Depression During the First COVID-19 Lockdown in France. Nat Sci Sleep, 2022;14:1545-1557
  • Klimes P, Peter-Derex L, Hall J, Dubeau F, Frauscher B. Spatio-temporal spike dynamics predict surgical outcome in adult focal epilepsy. Clin Neurophysiol., 2022;134:88-99.
  • Latreille V, Schiller K, Peter-Derex L, Frauscher B. Does epileptic activity impair sleep-related memory consolidation in epilepsy? A critical and systematic review. J Clin Sleep Med., 2022;18(10):2481-2495.
  • Nobili L, Frauscher B, Eriksson S, Gibbs SA, Halasz P, Lambert I, Manni R, Peter-Derex L, Proserpio P, Provini F, de Weerd A, Parrino L. Sleep and epilepsy: A snapshot of knowledge and future research lines. J Sleep Res., 2022;31(4):e13622.
  • Peter-Derex L, Philippeau F, Garnier P, André-Obadia N, Boulogne S, Catenoix H, Convers P, Mazzola L, Gouttard M, Esteban M, Fontaine J, Mechtouff L, Ong E, Cho TH, Nighoghossian N, Perreton N, Termoz A, Haesebaert J, Schott AM, Rabilloud M, Pivot C, Dhelens C, Filip A, Berthezène Y, Rheims S, Boutitie F, Derex L. Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Neurol., 2022;21(9):781-791.
  • Schiller K, Avigdor T, Abdallah C, Sziklas V, Crane J, Stefani A, Peter-Derex L, Frauscher B. Focal epilepsy disrupts spindle structure and function. Sci Rep., 2022;12(1):11137.
  • Chapoutot, M.; Peter-Derex, L.; Bastuji, H.; Leslie, W.; Schoendorff, B.; Heinzer, R.; Siclari, F.; Nicolas, A.; Lemoine, P.; Higgins, S.; Bourgeois, A.; Vallet, G.; Anders, R.; Ounnoughene, M.; Spencer, J.; Meloni, F.; Putois, B. Cognitive Behavioral Therapy and Acceptance and Commitment Therapy for the Discontinuation of Long-Term Benzodiazepine Use in Insomnia and Anxiety Disorders. Int. J. Environ. Res. Public Health, 2021, 18(19), 10222;
  • de la Chapelle A, Frauscher B, Valomon A, Ruby PM, Peter-Derex L. Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives. Front Neurosci., 2021 Sep 6;15:717078. doi: 10.3389/fnins.2021.717078. PMID: 34552464; PMCID: PMC8451887.
  • Des Champs de Boishebert L, Pradat P, Bastuji H, Ricordeau F, Gormand F, Le Cam P, Stauffer E, Petitjean T, Peter-Derex L. Microsleep versus Sleep Onset Latency during Maintenance Wakefulness Tests: Which One Is the Best Marker of Sleepiness? Clocks Sleep., 2021;3(2):259-273
  • Peter-Derex L, Berthomier C, Taillard J, Berthomier P, Bouet R, Mattout J, Brandewinder M, Bastuji H. Automatic analysis of single-channel sleep EEG in a large spectrum of sleep disorders. J Clin Sleep Med., 2021;17(3):393-402
  • Ruby P, Eskinazi M, Bouet R, Rheims S, Peter-Derex L. Dynamics of hippocampus and orbitofrontal cortex activity during arousing reactions from sleep: An intracranial electroencephalographic study. Hum Brain Mapp., 2021;42(16):5188-5203.
  • Frauscher B, von Ellenrieder N, Dolezalova I, Bouhadoun S, Gotman J, Peter-Derex L. Rapid Eye Movement Sleep Sawtooth Waves Are Associated with Widespread Cortical Activations. J Neurosci., 2020 ;40(46):8900-8912
  • Peter-Derex L, Derex L. Wake-up stroke: from pathophysiology to management. Sleep Med Rev., 2019; 48:101212.
  • Putois B, Peter-derex L, Leslie W, Braboszcz C, El Hage W, Bastuji H. Internet-based intervention for posttraumatic stress disorder: using remote Imagery Rehearsal Therapy to treat nightmares. Psychotherapy and Psychosomatics, 2019; 88:315-316. 
  • White M, Charbotel B, Fort E, Bastuji H, Franco P, Putois B, Mazza S, Peter-Derex L. Academic and professional paths of narcoleptic patients:  the Narcowork study. Sleep Medicine, 2020; 65:96-104
  • Flamand M, Boudet S, Lopes R, Vignal JP, Reyns N, Charley-Monaca C, Peter-Derex L, Szuthaj W. Confusional arousals ; evidence from intracerebral recordings. Sleep, 2018; 41(10)
  • Peter-Derex L, Catenoix H, Bastuji H, Chouchou F. Epilepsia or parasomnia : a matter of heart ? Neurophysiol Clin/Clin Neurophysiol, 2018; 48(5):277-286 
  • Peter-Derex L, Catenoix H, Bastuji H, Chouchou F. Parasomnia versus epilepsy: An affair of the heart? Neurophysiol Clin., 2018;48(5):277-286
  • Peter-Derex L., Magnin M. Bastuji, H. Heterogeneity of arousals in human sleep: a stereo-electroencephalographic study. Neuroimage, 2015; 123: 229-44.
  • Peter-Derex L, Comte JC, Mauguière F, Salin PA. Density and frequency caudo-rostral gradients of sleep spindles recorded in human cortex. Sleep, 2012; 35: 69-79.



Contact and Profil

E-mail professionnel : laure.peter-derex [at] or laure.peter-derex [at]

ResearchGate :